TRETINOIN FOR ACNE

Also known as all-trans-retinoic acid, tretinoin is the acid form of vitamin-A. It is a crystalline powder which is yellowish in color. Retinoic acid is soluble in DMSO, Polyethylene Glycol and Ethanol. It is practically insoluble in mineral oil and water.

How does Tretinoin works on acne?

In short, Tretinoin works by stimulating the skin cells to divide at a faster rate. Faster cell division means increased skin cell turnover rate causing the skin to peel which then promotes the extrusion of blackheads and whiteheads. Overall, the skin peeling unclogs blocked pores and exposes a new layer of younger skin cells. It may take 2 months or more of Tretinoin use to see an improvement in your acne.
Advantages
Reduction of the appearance of fine lines and wrinkles results as the layer of younger skin cells emerges at the surface.
Tretinoin also suppresses the pigment producing cells of the skin known as Melanocytes. The suppression of melanocytes reduces hyperpigmentation and results into an even skin tone.
Disadvantages
The main disadvantage of retinoid is that they cause photosensitivity. It makes the skin very sensitive to sunlight causing sunburns.
Takes several months to fully work.

Side Effects

During the 2 weeks of use, you would experience acne breakouts and flaking of the skin. Burning sensation, redness and peeling of the skin is expected. Lightening or darkening of the skin is also expected. As your skin adjusts to the medication, the side effects would gradually be lessened. This medication would also make your skin more sensitive to the sun. It is advisable to use sunblock (at least SPF15) when going out in areas where you are exposed to the sun otherwise your skin would be severely sunburned. In case of skin flaking, use a moisturizer to minimize flaking.
Dryness, redness or peeling may occur during the first weeks of treatment. To prevent aggravating the skin, protect it from sun, tanning lights, extreme wind or cold and harsh skincare products. Use of sunscreen is recommended.